British Air Force Typhoon jets have operated alongside France's air force in a combined operation targeting an underground arms cache in Syria operated by the IS group, according to the British defence ministry.
The site, located using reconnaissance, was thought to be housing weapons and explosive materials, the release indicated, and was situated in hills just above the ancient city of Palmyra in central Syria.
"Our aircraft used laser-guided Paveway IV weapons to hit a series of entry passages providing entry to the site... initial indications are that the objective was successfully hit," the ministry announced.
There was no sign of any civilian casualties in the strike late on Saturday and every plane involved returned safely, the ministry further stated.
The Typhoon fighters were assisted by a Voyager refuelling tanker.
Daesh - alternatively referred to as ISIS - imposed militant control over large swathes of Iraq and Syria until 2019.
"This operation demonstrates our UK leadership, and resolve to operate in unison with our allies, to eliminate any revival of Daesh and their violent and radical beliefs in the Middle East," UK Defence Secretary the Defence Secretary remarked.
UK warplanes have carried out patrols over Syria to "forestall any efforts to regroup" of IS subsequent to its defeat at the Baghuz confrontation in 2019, the ministry said.
"I extend gratitude to all the members of British forces who took part in this mission for their expertise and their bravery," he said. "They were among a great many UK service members deployed over Christmas and New Year. This operation, to remove militants who endanger our security, shows how British military are always on standby, continuously, keeping Britain secure at home and strong abroad."
Last December, the US military carried out what it called a "major assault" against Daesh sites in the country, following an assault killed two US servicemembers and a civilian linguist in the Palmyra area.
The United Nations says Daesh still boasts between 5,000 and 7,000 fighters in both countries.